Endo- and exocytic budding transformation of slow-diffusing membrane domains induced by Alzheimer's amyloid beta.
نویسندگان
چکیده
Cell-sized liposomes are a powerful tool for clarifying physicochemical mechanisms that govern molecular interactions. Herein, budding transformation of membrane domains was induced by amyloid beta peptides. The peptides increased the membrane viscosity as demonstrated by the Brownian motion of membrane domains. These results could aid in understanding the physicochemical mechanism of Alzheimer's disease.
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عنوان ژورنال:
- Physical chemistry chemical physics : PCCP
دوره 16 19 شماره
صفحات -
تاریخ انتشار 2014